"Flemoklav Solutab" thaum cev xeeb tub: cov lus qhia rau kev siv, noj, tshuaj xyuas
"Flemoklav Solutab" thaum cev xeeb tub: cov lus qhia rau kev siv, noj, tshuaj xyuas
Anonim

"Flemoclav Solutab" yog ib qho tshuaj tua kab mob nrog rau thaj tsam dav. Cov tshuaj pab tiv nrog mob khaub thuas, mob caj pas thiab pharyngitis. Zoo zam los ntawm cov neeg mob. Nws suav hais tias yog ib qho tshuaj tua kab mob zoo tshaj plaws. "Flemoklav Solutab" thaum cev xeeb tub kuj raug tso cai siv. Cov kev tshawb fawb tau pom tias cov tshuaj no tsis ua mob rau tus menyuam hauv plab thiab tsis cuam tshuam rau tus poj niam cev xeeb tub.

"Flemoklav Solutab": cov tshuaj muaj pes tsawg leeg

Cov tshuaj no tsuas muaj nyob rau hauv cov ntsiav tshuaj xwb. Cov tshuaj yog oblong dawb nrog me ntsis yellowish tint. Lawv yog tsim nyob rau hauv ntau yam concentrations. Tej zaum yuav muaj nyob rau hauv kev npaj "Flemoklav Solutab" 125 mg ntawm amoxicillin thiab 31.25 mg ntawm clavulanic acid (clavulanic acid). Cov ntsiav tshuaj tau tsim muaj 250, 500 mg ntawm amoxicillin thiab 62, 5, 125 mg ntawm clavulanate, feem. Feem ntauIb qho loj ntawm cov khoom xyaw nquag yog nyob rau hauv cov tshuaj "Flemoklav Solutab" 875/125 (thaum cev xeeb tub, daim ntawv tso tawm no tsis tshua muaj los ntawm kws kho mob), qhov twg 875 mg ntawm amoxicillin thiab 125 mg ntawm clavulanic acid..

Cov tshuaj thib ob ntawm cov ntsiav tshuaj yog microcrystalline cellulose, vanillin, magnesium stearate, crospovidone, saccharin, apricot fragrance. Cov ntsiav tshuaj tau ntim rau hauv txhuas hlwv ntawm 4 lossis 7 daim. Lub pob tuaj yeem muaj los ntawm 14 txog 20 ntsiav tshuaj.

Cov tshuaj yog muab los ntawm cov khw muag tshuaj yam tsis muaj kws kho mob sau ntawv. Lub txee lub neej ntawm cov khoom siv tshuaj yog peb xyoos txij li hnub tsim khoom. Cov tshuaj yuav tsum tau khaws cia rau hauv qhov chaw qhuav thiab txias, tiv thaiv kom zoo los ntawm cov menyuam yaus, ntawm qhov kub txog +25˚С.

Pharmacological kev txiav txim ntawm cov tshuaj

"Flemoklav Solutab" thaum cev xeeb tub yog ntau zaus. Qhov no yog cov tshuaj tua kab mob maj mam tshaj plaws ntawm penicillin series. Hais txog beta-lactamase inhibitors. Cov tshuaj yog ua ke thiab muaj ob yam khoom xyaw nquag. Cov no yog amoxicillin thiab clavulanate. Ntau tus neeg mob txaus siab rau lo lus nug: "Amoxicillin yog tshuaj tua kab mob lossis tsis yog?" Lo lus teb rau nws yog unequivocal. Amoxicillin yog tshuaj tua kab mob thiab feem ntau siv los kho cov kab mob ua pa, kab mob, thiab kis kab mob.

Cov tshuaj no muaj cov kab mob bactericidal ntawm lub cev. Nws inhibits phab ntsa ntawm cov kab mob. Nws qhia tau hais tias nws cov dej num tiv thaiv cov kab mob gram-negative thiab gram-positive microorganisms. Qhov no suav nrog cov kab mob uas tsim cov beta-lactamases. Cov tshuaj tua kab mob muaj clavulanic acid.kua qaub. Vim li cas cov khoom no muaj nyob rau hauv cov tshuaj tua kab mob? Ua ntej tshaj plaws, clavulanic acid inhibits hom II, III, IV thiab V ntawm beta-lactamases, tab sis tsis qhia nws cov haujlwm tiv thaiv hom I beta-lactamases. Ua tiav nws cov txiaj ntsig ua ke nrog penicillins. Kev sib xyaw ua ke no tiv thaiv kev degradation ntawm amoxicillin raws li kev cuam tshuam ntawm beta-lactamases. Kev nthuav dav thaj tsam ntawm qhov tshwm sim ntawm cov tshuaj.

Flemoklav solutab thaum cev xeeb tub
Flemoklav solutab thaum cev xeeb tub

Lub bioavailability ntawm amoxicillin yog 94%. Kev nqus ntawm cov tshuaj nquag tsis cuam tshuam los ntawm kev noj zaub mov. Qhov siab tshaj plaws ntawm amoxicillin hauv plasma yog pom tom qab ob peb teev. Tom qab ib koob tshuaj ntawm ib ntsiav tshuaj nrog ib koob tshuaj ntawm 500/125 mg, tom qab yim teev, qhov nruab nrab ntawm amoxicillin yog 0.3 mg / l. Cov khoom no cuam tshuam nrog cov protein los ntawm 17-20%. Nws muaj peev xwm hla lub placenta. Me me muaj nyob hauv cov kua mis.

Amoxicillin yog 10% metabolized nyob rau hauv lub siab. Kwv yees li 50% ntawm cov tshuaj yog tawm los ntawm lub raum. Tus so ntawm cov tshuaj yog excreted nyob rau hauv cov kua tsib. Kev tshem tawm ib nrab-lub neej hauv cov neeg mob uas tsis muaj teeb meem rau lub raum thiab lub siab yog rau teev. Yog hais tias tus neeg mob raug kev txom nyem los ntawm anuria, ib nrab-lub neej nce mus rau 10-12 teev. Cov tshuaj yuav raug tso tawm thaum lub sij hawm hemodialysis.

Bioavailability ntawm clavulanate yog 60%. Cov txheej txheem nqus dej tsis cuam tshuam los ntawm kev noj zaub mov. Qhov siab tshaj plaws ntawm cov tshuaj nquag no hauv cov ntshav tau pom ob teev tom qabkev siv cov ntsiav tshuaj. Yog tias koj noj cov ntsiav tshuaj "Flemoklav Solutab" 125/500 mg (clavulanate / amoxicillin), tom qab yim teev qhov siab tshaj plaws ntawm clavulanic acid yuav yog 0.08 mg / l. Clavulanate yog 22% khi rau cov ntshav proteins. Nws ywj siab nkag mus rau placental barrier. Cov ntaub ntawv hais txog kev nkag mus ntawm cov tshuaj no rau hauv cov kua mis tsis muaj.

Clavulanic acid yog metabolized los ntawm 50-70% hauv cov kab mob siab. Kwv yees li 40% ntawm cov khoom no yog tawm los ntawm lub raum. Ib nrab neej - 60 feeb.

Cov lus qhia rau kev siv cov ntsiav tshuaj

"Flemoklav Solutab" thaum cev xeeb tub tuaj yeem raug tshuaj rau cov neeg mob thaum muaj xwm txheej ceev. Cov lus qhia rau kev siv cov tshuaj no yog cov kab mob ntawm ib tug kab mob thiab inflammatory dab, pathologies ntawm lub Upper pa ib ntsuj av tau, kab mob ntawm cov kab mob ENT, ntawm lawv - sinusitis, pharyngitis, otitis media, tonsillitis. Cov tshuaj no yog muab rau cov pathologies ntawm lub sab ua pa ib ntsuj av tau, thaum kuaj pom muaj bronchitis los yog mob ntsws nyob rau hauv zej zog. Ntxiv mus, cov tshuaj yog noj ob qho tib si nyob rau hauv mob thiab nyob rau hauv lub sij hawm ntev ntawm kev loj hlob ntawm tus kab mob. Cov tshuaj yog muab rau cov kab mob sib kis ntawm daim tawv nqaij thiab cov nqaij mos, kab mob ntawm lub genitourinary system thiab lub raum kab mob.

Nrog ceev faj heev, cov ntsiav tshuaj tau muab tshuaj rau lub raum thiab lub siab tsis txaus. Nrog pathologies ntawm lub plab hnyuv apparatus, nrog rau thaum muaj keeb kwm ntawm colitis.

Daim ntawv thov

Flemoklav Solutab 125
Flemoklav Solutab 125

"Flemoklav Solutab" thaum cev xeeb tub raug tshuaj thaum kho tshuaj tua kab mob tseem ceebpoj niam, thiab cov tshuaj maj mam tsis pab. Hauv lwm lo lus, raws li qhov chaw kawg. Raws li qhov tshwm sim ntawm ntau cov kev tshawb fawb, nws tau pom tias cov tshuaj tsis muaj cov kab mob pathogenic rau kev loj hlob ntawm tus me nyuam hauv plab thiab ntawm tus mob ntawm tus menyuam mos. Kev siv cov ntsiav tshuaj no hauv II thiab III trimester yog suav tias yog kev nyab xeeb. "Flemoklav Solutab" thaum lub sij hawm cev xeeb tub nyob rau hauv lub peb hlis ntuj 1 yog muab nrog ceev faj heev.

Cov tshuaj no tau pom zoo siv thaum lactation. Txawm hais tias qhov tseeb tias amoxicillin nkag mus rau hauv cov kua mis, nws tsis muaj qhov tsis zoo rau tus menyuam. Kev sib xyaw ua ke ntawm cov tshuaj xws li amoxicillin thiab clavulanic acid tsis cuam tshuam rau tus menyuam.

YContraindications

Flemoclav Solutab tsis raug tshuaj rau kev mob siab rau cov khoom uas tshwm sim hauv cov tshuaj muaj pes tsawg leeg. Tsis txhob muab tshuaj rau cov tshuaj tiv thaiv kab mob siab rau beta-lactam tshuaj tua kab mob, tshuaj cephalosporin thiab hypersensitivity rau penicillins.

Amoxicillin yog tshuaj tua kab mob lossis tsis yog
Amoxicillin yog tshuaj tua kab mob lossis tsis yog

Kev txwv tsis pub siv cov tshuaj yog kev ua haujlwm tsis zoo ntawm lub siab lub cev, jaundice, uas thaum lub sijhawm noj "Flemoclav Solutaba" yog keeb kwm. Hauv cov neeg mob uas kuaj pom muaj lymphocytic leukemia thiab kis kab mob mononucleosis, qhov tshwm sim ntawm exanthema nce. Vim li no, kev sib xyaw ntawm amoxicillin nrog clavulanate yuav tsum tsis txhob raug tshuaj rau cov mob no.

"Flemoklav Solutab": cov lus qhia rau kev siv thaum cev xeeb tub

Txhawm rau kho "FlemoklavSolutab" txhawm rau tshem tawm cov tsos mob dyspeptic, koj yuav tsum noj cov tshuaj thaum pib noj mov. Cov ntsiav tshuaj yuav tsum tau nqos tag nrho nrog dej. Yog hais tias lub ntsiav tshuaj yog ib qho nyuaj rau nqos, ces koj muaj peev xwm yaj nws nyob rau hauv 100 g ntawm dej thiab haus cov resulting tov.

Lub sijhawm kho mob cuam tshuam los ntawm qhov mob hnyav. Kev kho mob yuav tsum tsis pub tshaj 14 hnub.

Cov poj niam cev xeeb tub, cov neeg laus thiab cov menyuam yaus uas hnyav tshaj 40 kg yog muab 500 mg / 125 mg peb zaug ib hnub. Yog tias tus kab mob hnyav heev, tau mob ntev los yog nrog cov teeb meem, ces qhov koob tshuaj yog ob npaug.

Vim li cas clavulanic acid siv hauv tshuaj tua kab mob?
Vim li cas clavulanic acid siv hauv tshuaj tua kab mob?

Cov koob tshuaj "Flemoklava Solutab" thaum cev xeeb tub yuav tsum tsis pub tshaj qhov pom zoo saum toj no. Kev siv cov tshuaj nyob rau hauv II thiab III trimesters yog ua tom qab kev soj ntsuam cov txiaj ntsig ntawm cov tshuaj rau leej niam thiab qhov muaj feem cuam tshuam rau tus menyuam. Cov poj niam cev xeeb tub yuav tsum tsis txhob noj 875 mg / 125 mg ntsiav tshuaj. Cov ntsiav tshuaj nrog cov ntsiab lus ntawm cov khoom xyaw nquag 125 mg / 31.25 mg, 250 mg / 62.5 mg, 500 mg / 125 mg tuaj yeem siv rau txhua lub sijhawm cev xeeb tub. Hauv thawj peb lub hlis twg, cov ntsiav tshuaj no tau noj nrog ceev faj heev.

Cov menyuam yaus hnub nyoog 2 txog 12 xyoos, nws qhov hnyav li ntawm 13-37 kg, tau muab tshuaj amoxicillin ib hnub ntawm 20-30 mg thiab clavulanate ntawm koob tshuaj 5-7.5 mg. Tus nqi ntawm cov tshuaj no yog xam rau 1 kg ntawm lub cev hnyav ntawm tus menyuam. Raws li txoj cai dav dav, nruab nrab ntawm cov hnub nyoog 2 txog 7 xyoo, cov menyuam mos tau muab ib ntsiav tshuaj ntawm 125/31, 25mg peb zaug ib hnub.

Bhnub nyoog qeb los ntawm xya mus rau kaum ob xyoos, cov tshuaj tau sau ib ntsiav tshuaj 250/62, 5 mg peb zaug ib hnub twg. Yog tias muaj cov kab mob sib kis hnyav, ces qhov koob tshuaj yog ob npaug. Qhov siab tshaj plaws tau koob tshuaj rau tus menyuam yog 60 mg ntawm amoxicillin thiab 15 mg ntawm clavulanate, xam rau 1 kg ntawm qhov hnyav.

Cov menyuam yaus hnub nyoog 3 hlis txog rau ob xyoos uas hnyav 5-12 kg yog muab 20-30 mg ntawm amoxicillin thiab 5-7.5 mg ntawm clavulanate ib kilogram ntawm tus menyuam qhov hnyav. Qhov no feem ntau yog ib koob ntawm 125/31.25 yuav tsum tau noj ob zaug ib hnub.

Nyob rau hauv cov neeg mob uas muaj lub raum tsis ua haujlwm, kev tso tawm ntawm cov tshuaj no qeeb, yog li lawv txoj kev kho mob raws li hauv qab no:

Yog tias GFR (glomerular filtration rate) yog 10-30 ml / min, ces cov tshuaj amoxicillin rau cov neeg laus yog 500 mg ob zaug ib hnub, rau cov menyuam yaus - 15 mg / kg noj ob zaug ib hnub.

GFR tshaj 10 ml / min. koob tshuaj amoxicillin rau cov neeg laus yog 500 mg ib hnub twg, rau cov menyuam yaus - 15 mg / kg ib hnub.

Cov neeg laus ntawm hemodialysis tau muab tshuaj amoxicillin 500 mg txhua hnub, 500 mg thaum lub sijhawm lim ntshav, thiab 500 mg tom qab ntawd.

Cov neeg mob uas muaj kev ua haujlwm tsis zoo ntawm lub siab lub cev, cov tshuaj tau muab tshuaj nrog ceev faj heev. Thaum noj Flemoclav Solutab, cov neeg mob no yuav tsum nyob hauv kev tswj hwm ntawm tus kws kho mob uas ua tib zoo saib xyuas lub siab ua haujlwm.

Side effects

Flemoklav solutab
Flemoklav solutab

Cov lus qhia rau kev siv "Flemoclav Solutab" thaum cev xeeb tub yog tib yam li rau lwm tus neeg. Thaum cov tshuaj no yog noj los ntawm cov poj niam cev xeeb tub, cov neeg laus, thiabCov menyuam yaus qee zaum muaj kev cuam tshuam tsis zoo ntawm lub cev.

Qhov no feem ntau yog kev ua xua, uas tshwm sim nws tus kheej hauv daim ntawv ntawm urticaria, erythematous ua pob, dermatitis, Stevens-Johnson syndrome. Hauv cov xwm txheej sib cais, qhov burrow zoo li exanthema tuaj yeem tshwm sim. Cov kev tshwm sim ntawm lub cev nyob ntawm seb tus neeg mob tus mob, qhov hnyav ntawm tus kab mob thiab qhov ntau npaum li cas.

Thaum noj cov ntsiav tshuaj Flemoklav Solutab, qhov tshwm sim tsis zoo ntawm lub plab zom mov tuaj yeem ua tau. Lawv manifest lawv tus kheej nyob rau hauv daim ntawv ntawm xeev siab, gag reflex, kab mob ntawm cov kab mob siab, nce kev ua ntawm "siab" transaminases. Tsis tshua muaj txaus, cholestatic jaundice, colitis thiab kab mob siab tshwm sim thaum noj cov tshuaj no.

Thaum noj tshuaj, muaj qhov nce hauv alkaline phosphatase, transaminase (ACT thiab ALT), bilirubin hauv cov txiv neej thiab cov neeg laus dua 65.

Ntawm lwm yam kev phiv ntawm lub cev, candidiasis, nce lub sijhawm prothrombin thiab kev loj hlob tau pom.

Kev noj tshuaj ntau dhau yuav ua rau ntuav, raws plab, xeev siab thiab lwm yam kab mob plab hnyuv. Muaj peev xwm ua txhaum ntawm electrolyte thiab dej metabolism.

Yog cov tsos mob tshwm sim ntau dhau, cov hluav taws xob hluav taws xob tau muab tshuaj. Yog hais tias convulsions tshwm sim, diazepam yog tshuaj. Qhov tshwm sim ntawm lwm yam tsis zoo tshwm sim yog kho symptomatically. Yog tias lub raum tsis ua haujlwm, ces hemodialysis tau ua.

cov lus qhia dav dav

Flemoklav solutab muaj pes tsawg leeg ntawm cov tshuaj
Flemoklav solutab muaj pes tsawg leeg ntawm cov tshuaj

Ntau tus neeg mob, pom qhov muaj pes tsawg leeg ntawm Flemoklav Solutab, nug lawv tus kheej:"Amoxicillin yog tshuaj tua kab mob lossis tsis?" Yog lawm, cov tshuaj no, zoo li cov khoom xyaw nquag amoxicillin, yog cov tshuaj tua kab mob ntawm cov tshuaj penicillin series.

Nyob rau hauv cov neeg mob hypersensitivity rau lub Cheebtsam ntawm cov tshuaj no, ib tug anaphylactic tshuaj tiv thaiv yuav tshwm sim. Kev kho mob hauv qhov no yuav tsum tau muab tshem tawm sai sai thiab tus neeg mob yuav tsum tau muab tshuaj kho kom tsim nyog. Txhawm rau tshem tawm anaphylactic poob siab, kev txhaj tshuaj ntawm adrenaline thiab corticosteroids yog qhov xav tau ceev.

Muaj qhov muaj peev xwm ua rau muaj qhov tsis txaus ntseeg thiab tiv thaiv kab mob rau cephalosporins thiab lwm yam penicillins. Raws li nrog rau kev siv lwm yam tshuaj tua kab mob, thaum noj Flemoclav Solutab, kab mob thiab fungal kab mob, nrog rau candidiasis, tej zaum yuav tshwm sim. Thaum superinfections tshwm sim, cov tshuaj raug tso tseg, thiab kev kho mob raug tshuaj xyuas.

Nyob hauv qee zaus, muaj qhov nce ntawm lub sijhawm prothrombin. "Flemoklav Solutab" yog sau nrog ceev faj rau cov neeg mob uas tau txais kev kho mob anticoagulation.

Txoj kev tsis yog enzymatic rau kev txiav txim siab cov piam thaj hauv cov zis, nrog rau kev sim rau urobilinogen, tuaj yeem muab cov txiaj ntsig tsis zoo.

"Flemoklav Solutab" muaj clavulanic acid. Nws qhia me ntsis kev ua haujlwm tawm tsam enterococci thiab Pseudomonas aeruginosa. Muaj feem cuam tshuam rau Haemophilus influenzae thiab Enterobacteriaceae. Rau ntau dua, cov tshuaj muaj zog tiv thaiv kab mob bacteroids, streptococci, moraxella thiab staphylococci. Cov tshuaj beta-lactam muaj txiaj ntsig zoo tiv thaiv legionella thiab chlamydia. Nov yog yam tshuaj tua kab mob clavulanic rauacid yog tam sim no. Nws nthuav lawv txoj kev ncav cuag thiab txhim kho lawv cov txiaj ntsig.

Tus nqi

Flemoklav solutab thaum cev xeeb tub
Flemoklav solutab thaum cev xeeb tub

Cov tshuaj "Flemoklav Solutab" tuaj yeem yuav yam tsis muaj teeb meem ntawm lub tsev muag tshuaj. Nws raug tso tawm yam tsis muaj kws kho mob sau ntawv. Nws raug nqi li ntawm 400 rubles rau 20 ntsiav tshuaj. Tus nqi, nyob ntawm qhov cim ntawm qhov hluav taws xob, yuav txawv me ntsis.

Kev tshuaj xyuas cov poj niam cev xeeb tub

Kev tshuaj xyuas txog "Flemoclav Solutab" thaum cev xeeb tub feem ntau yog qhov zoo. Cov poj niam nco ntsoov tias thaum kho lawv tsis muaj kev phiv tshuaj. Cov tshuaj tiv thaiv tau zoo. Nws pab ntau tus poj niam nyob rau hauv txoj hauj lwm los kho purulent tonsillitis, hnoos ntev ntev, cystitis. Feem ntau yog tshuaj rau mob khaub thuas, SARS thiab sinusitis. Hauv txhua qhov xwm txheej saum toj no, nws pom nws tus kheej tsuas yog ntawm qhov zoo thiab tsis ua rau muaj qhov tsis zoo.

Qhov teeb meem rau poj niam tsuas yog qhov loj ntawm cov tshuaj. Raws li lawv, nrog angina nws yog ib qho nyuaj rau haus lawv. Vim li no, ntau tus poj niam dilute cov tshuaj hauv dej thiab noj cov tshuaj ua kua.

Txhua qhov xwm txheej, thaum cov tshuaj tau muab rau cov poj niam cev xeeb tub, nws zoo kawg nkaus ua haujlwm thiab tsis ua rau muaj kev tsis txaus siab los ntawm cov neeg mob.

Pom zoo: